We pray with our hands and often communicate with them. We use them to eat, work, and make love. We employ them as marvelous sophisticated instruments of flexibility and strength, and when they are damaged, we anguish. (3)
The hand is composed of many small bones called carpals, metacarpals and phalanges. The two bones of the lower arm -- the radius and the ulna -- meet at the hand to form the wrist.
The carpal bones are a set of eight short bones forming the wrist; they are disposed on two rows of four bones each. These bones, the size of a marble, provide the wrist's litheness and mobility.
The palm of the hand is composed of five metacarpal bones laid out from the wrist, as a fan. The articulation of the first metacarpal bone with the carpal bones, permits the movement of touching, with the thumb, the tips of all fingers.

It is from this movement that the human hand can acquire the efficiency necessary to grab and manipulate objects.

Every hand is composed of 14 long bones named the phalanges. These bones compose the fingers and the thumb. Each finger has three phalanges and the thumb only two.
Next
(5)
(4)
The bones
The muscles
The intrisic muscles of the hand are divided into three groups: (1) the thumb or thenar muscles, (2) the little finger or the hypothenar muscles, and (3) the lumbrical muscles. With the lumbrical muscles are the long flexor tendons, which are the extrinsic muscles of the hand.
(5)
The nerves and blood vessels
The Median and Ulnar nerves are the major nerves of the hand, running the length of the arm to transmit electrical impulses to and from the brain to create movement and sensation.
Because of the importance of manual dexterity in occupational and recreational activities, it is essential to know and maintain the structure and function of the hand. There exists many diseases and malformations of the hand that can be extremely upsetting. One commonly known example is of course arthritis. Other examples include Dupuytren's Disease, De Quervain's Disease, Triangular Fibrocartilage Complex, Carpal Tunnel Syndrome ... and the list goes on.
Hand facts
Each hand contains (plus or minus... everyone is different, and everyone counts these things differently...)

29 major and minor bones (many people have a few more).

29 major joints.

At least 123 named ligaments.

34 muscles which move the fingers and thumb:

17 in the palm of the hand, and 18 in the forearm.

48 named nerves:3 major nerves.

24 named sensory branches. 21 named muscular branches.

30 named arteries and nearly as many smaller named branches.(5)

The muscles which power the fingers are strong - strong enough for some people to climb vertical surfaces supporting their entire weight at times by a few fingertips. The muscles which accomplish this feat are stronger than you might imagine, for the biomechanics of the hand require that the force generated by the muscles which bend the fingertips must be at least four times the pressure which is produced at the fingertips.(5)
The skin on the palm side of the hand and fingers is unique for these reasons and more:

No hair (the medical term is glabrous).

Fingerprints.

Usually neither color nor the ability to tan.

Tough and durable, yet sensitive.

Anchored down to the bones beneath through an intermediate layer of fascia. This arrangement keeps the skin of the palm from sliding around like a rubber glove when we use our hands to grip and twist.

In some people, this layer of fascia shrinks and thickens, leading to Dupuytren's disease.(5)

1-
2-
3-